/* ==========================================================================
   Simulateur PK — Méthylphénidate
   Feuille de style principale
   ========================================================================== */

:root {
    --primary-color:   #2c3e50;
    --secondary-color: #3498db;
    --accent-color:    #5dade2;
    --success-color:   #27ae60;
    --warning-color:   #f39c12;
    --danger-color:    #e74c3c;
    --info-color:      #8e44ad;
    --light-bg:        #ecf0f1;
    --card-bg:         #ffffff;
    --text-dark:       #2c3e50;
    --text-muted:      #7f8c8d;
    --border-light:    #dee2e6;

    --strat-a-color:   #3498db;
    --strat-b-color:   #e67e22;
    --strat-a-bg:      #eaf4fb;
    --strat-b-bg:      #fdf2e9;
}

* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

body {
    font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Oxygen, Ubuntu, sans-serif;
    line-height: 1.6;
    color: var(--text-dark);
    background-color: #f5f7fa;
    padding: 20px;
    min-height: 100vh;
}

.container {
    max-width: 1300px;
    margin: 0 auto;
    background-color: var(--card-bg);
    border-radius: 10px;
    box-shadow: 0 2px 10px rgba(0, 0, 0, 0.08);
    padding: 40px;
}

/* -------- Warning banner ------------------------------------------------- */
.warning-banner {
    background-color: #fdecea;
    color: #722b27;
    border-left: 5px solid var(--danger-color);
    padding: 14px 20px;
    border-radius: 6px;
    margin-bottom: 25px;
    font-size: 0.95em;
    line-height: 1.5;
}

.warning-banner strong {
    color: var(--danger-color);
}

/* -------- Header --------------------------------------------------------- */
header {
    text-align: center;
    margin-bottom: 30px;
    padding-bottom: 20px;
    border-bottom: 3px solid var(--secondary-color);
}

header h1 {
    color: var(--primary-color);
    font-size: 1.9em;
    margin-bottom: 8px;
}

.subtitle {
    color: var(--text-muted);
    font-style: italic;
    font-size: 0.95em;
}

/* -------- Patient info --------------------------------------------------- */
.patient-info {
    background-color: var(--light-bg);
    padding: 20px;
    border-radius: 8px;
    margin-bottom: 20px;
}

.patient-info h2 {
    color: var(--primary-color);
    font-size: 1.25em;
    margin-bottom: 15px;
    padding-bottom: 8px;
    border-bottom: 2px solid var(--secondary-color);
}

.form-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(180px, 1fr));
    gap: 15px;
}

.form-group {
    display: flex;
    flex-direction: column;
}

.form-group label {
    font-weight: 600;
    margin-bottom: 5px;
    color: var(--text-dark);
    font-size: 0.9em;
}

.form-group input,
.form-group select {
    padding: 8px 10px;
    border: 1px solid var(--border-light);
    border-radius: 5px;
    font-size: 0.95em;
    background-color: #ffffff;
    font-family: inherit;
    color: var(--text-dark);
    transition: border-color 0.15s, box-shadow 0.15s;
}

.form-group input:focus,
.form-group select:focus {
    outline: none;
    border-color: var(--secondary-color);
    box-shadow: 0 0 0 3px rgba(52, 152, 219, 0.15);
}

/* -------- Setup row (poids + mode sur une même ligne) ------------------- */
.setup-row {
    display: grid;
    grid-template-columns: repeat(12, 1fr);
    gap: 14px 16px;
    align-items: stretch;
    background-color: var(--light-bg);
    padding: 14px 18px;
    border-radius: 8px;
    margin-bottom: 20px;
}

.setup-block {
    display: flex;
    flex-direction: column;
    gap: 6px;
    min-width: 0;
    height: 100%;
}

.setup-block .mode-toggle {
    flex: 1;
    align-items: stretch;
    flex-wrap: nowrap;
}

.setup-block .mode-option {
    min-height: 44px;
    min-width: 0;
    flex: 1 1 0;
}

/* Ligne 1 : Poids (1) + Sexe (3) + Mode (5) + Modèle PK (3) = 12 */
.setup-weight     { grid-column: span 1; min-width: 80px; }
.setup-sex        { grid-column: span 3; }
.setup-mode       { grid-column: span 5; }
.setup-engine     { grid-column: span 3; }

/* Ligne 2 : Standard d'affichage (6) + Options (6) = 12 */
.setup-reporting  { grid-column: span 6; }
.setup-display    { grid-column: span 6; }

/* Ligne 3 : Variabilité interindividuelle = 12 */
.setup-variability { grid-column: span 12; }

.setup-weight label,
.setup-label {
    font-weight: 600;
    font-size: 0.9em;
    color: var(--text-dark);
}

.setup-weight input {
    padding: 10px 12px;
    border: 1px solid var(--border-light);
    border-radius: 6px;
    font-size: 0.95em;
    background-color: #ffffff;
    font-family: inherit;
    color: var(--text-dark);
    transition: border-color 0.15s, box-shadow 0.15s;
    width: 100%;
    min-height: 44px;
    text-align: center;
    box-sizing: border-box;
}

.setup-weight input:focus {
    outline: none;
    border-color: var(--secondary-color);
    box-shadow: 0 0 0 3px rgba(52, 152, 219, 0.15);
}

/* Tablette : ramener à 2 colonnes par ligne */
@media (max-width: 1024px) {
    .setup-weight     { grid-column: span 3; }
    .setup-sex        { grid-column: span 9; }
    .setup-mode,
    .setup-engine,
    .setup-reporting  { grid-column: span 6; }
    .setup-display    { grid-column: span 12; }
}

/* Mobile : une colonne unique */
@media (max-width: 640px) {
    .setup-weight,
    .setup-sex,
    .setup-mode,
    .setup-engine,
    .setup-reporting,
    .setup-display,
    .setup-variability { grid-column: span 12; }
}

/* -------- Mode selector (legacy rules still applied to .mode-toggle) ---- */
.mode-selector {
    background-color: #f8fbfe;
    border: 1px solid var(--border-light);
    padding: 18px 20px;
    border-radius: 8px;
    margin-bottom: 20px;
}

.mode-selector h2 {
    color: var(--primary-color);
    font-size: 1.15em;
    margin-bottom: 12px;
}

.mode-toggle {
    display: flex;
    gap: 10px;
    flex-wrap: wrap;
    margin-bottom: 0;
}

.mode-option {
    flex: 1;
    min-width: 160px;
    display: flex;
    align-items: center;
    gap: 8px;
    padding: 8px 12px;
    border: 1px solid var(--border-light);
    border-radius: 6px;
    background-color: var(--card-bg);
    cursor: pointer;
    font-weight: 500;
    font-size: 0.95em;
    transition: background-color 0.15s, border-color 0.15s;
}

.mode-option:hover {
    background-color: var(--light-bg);
}

.mode-option input[type="radio"],
.mode-option input[type="checkbox"] {
    accent-color: var(--secondary-color);
    cursor: pointer;
}

.mode-option:has(input:checked) {
    border-color: var(--secondary-color);
    background-color: #eaf4fb;
    box-shadow: 0 0 0 2px rgba(52, 152, 219, 0.15);
}

.mode-option.mode-checkbox:has(input:checked) {
    border-color: #27ae60;
    background-color: #eafaf0;
    box-shadow: 0 0 0 2px rgba(39, 174, 96, 0.18);
}

.mode-help {
    font-size: 0.85em;
    color: var(--text-muted);
    font-style: italic;
    margin: 0;
}

/* -------- Consignes ------------------------------------------------------ */
.consignes {
    background-color: #fff8e1;
    border-left: 4px solid var(--warning-color);
    padding: 15px 20px;
    margin-bottom: 25px;
    border-radius: 4px;
}

.consignes h2 {
    color: var(--primary-color);
    font-size: 1.15em;
    margin-bottom: 10px;
}

.consignes p {
    margin-bottom: 8px;
    font-size: 0.95em;
}

.consignes p:last-child {
    margin-bottom: 0;
}

.consignes ol {
    margin: 8px 0 10px 22px;
    padding: 0;
}

.consignes ol li {
    margin-bottom: 4px;
    font-size: 0.95em;
    line-height: 1.45;
}

.consignes-note {
    font-size: 0.9em;
    font-style: italic;
    color: var(--text-muted);
}

.consignes-note a {
    color: var(--primary-color);
    text-decoration: underline;
}

.equi-table {
    width: 100%;
    max-width: 100%;
    border-collapse: collapse;
    margin: 12px 0;
    font-size: 0.95em;
    border: 2px solid #546e7a;
}

.equi-table th,
.equi-table td {
    border: 1px solid #90a4ae;
    padding: 8px 10px;
    text-align: center;
    vertical-align: middle;
}

.equi-table thead th {
    background-color: #e8f0fe;
    color: var(--text-color, #222);
    font-weight: 600;
    border: 1px solid #546e7a;
}

.equi-table tbody tr:nth-child(even) {
    background-color: #f7fafd;
}

/* Trait épais entre la colonne molécule / bloc iso-AUC / bloc ANSM */
.equi-table th:first-child,
.equi-table td:first-child {
    border-right: 2px solid #546e7a;
    font-weight: 600;
    background-color: #eceff1;
}

.equi-table thead tr:first-child th:nth-child(2),
.equi-table thead tr:last-child th:nth-child(3),
.equi-table tbody td:nth-child(3) {
    border-right: 2px solid #546e7a;
}

/* Trait épais entre l'en-tête et le corps */
.equi-table thead {
    border-bottom: 2px solid #546e7a;
}

/* Tableau galénique : colonnes alignées à gauche, codage couleur OK/KO */
.galenique-table th,
.galenique-table td {
    text-align: left;
}

.galenique-table tbody tr.ok td:nth-child(3) {
    color: #1b5e20;
    font-weight: 600;
}

.galenique-table tbody tr.ko td:nth-child(3) {
    color: #b71c1c;
    font-weight: 600;
}

.galenique-table tbody tr.ko {
    background-color: #fdecea;
}

.galenique-table tbody tr.ko:nth-child(even) {
    background-color: #fce4e0;
}

/* Désactive le fond gris de la première colonne pour ce tableau */
.galenique-table th:first-child,
.galenique-table td:first-child {
    background-color: transparent;
}

.galenique-table tbody tr.ko td:first-child {
    background-color: transparent;
}

.equi-sub {
    display: block;
    font-size: 0.82em;
    font-weight: 400;
    font-style: italic;
    color: var(--text-muted);
    margin-top: 2px;
}

/* -------- Model details (explanations) ---------------------------------- */
.model-details {
    margin-top: 30px;
    padding: 20px 24px;
    background-color: #f5f9ff;
    border-left: 4px solid var(--primary-color);
    border-radius: 4px;
}

.model-details h2 {
    color: var(--primary-color);
    margin-bottom: 12px;
}

.model-details h3 {
    margin-top: 18px;
    margin-bottom: 8px;
    color: var(--primary-color);
    font-size: 1.05em;
}

.model-details h4 {
    margin-top: 12px;
    margin-bottom: 6px;
    font-size: 0.98em;
    color: var(--text-color, #333);
}

.model-details p,
.model-details li {
    font-size: 0.92em;
    line-height: 1.5;
}

.model-details ul {
    margin: 6px 0 10px 22px;
    padding: 0;
}

.model-details li {
    margin-bottom: 4px;
}

.model-details .model-note {
    margin-top: 4px;
    padding: 8px 12px;
    background-color: #eaf4fb;
    border-left: 3px solid var(--secondary-color);
    border-radius: 3px;
    font-size: 0.88em;
    font-style: italic;
}

.model-details .formula {
    margin: 8px 0;
    padding: 10px 14px;
    background-color: #f4f6f8;
    border-left: 3px solid #546e7a;
    border-radius: 3px;
    font-family: "Cambria Math", "Latin Modern Math", "Times New Roman", serif;
    font-size: 1.02em;
    text-align: center;
    overflow-x: auto;
}

/* Codage couleur pour la table de validation externe */
.val-good {
    color: #1b5e20;
    font-weight: 600;
    background-color: #e8f5e9;
    padding: 1px 6px;
    border-radius: 3px;
}

.val-acceptable {
    color: #e65100;
    font-weight: 600;
    background-color: #fff3e0;
    padding: 1px 6px;
    border-radius: 3px;
}

.val-warn {
    color: #b71c1c;
    font-weight: 600;
    background-color: #fdecea;
    padding: 1px 6px;
    border-radius: 3px;
}

.pk-summary td.val-cell {
    padding: 8px 10px;
    border-radius: 0;
    line-height: 1.35;
}

.pk-summary td.val-cell.val-good {
    background-color: #e8f5e9;
}

.pk-summary td.val-cell.val-acceptable {
    background-color: #fff3e0;
}

.pk-summary td.val-cell.val-warn {
    background-color: #fdecea;
}

.validation-mean-table td {
    vertical-align: top;
}

.mean-hit,
.mean-near,
.mean-high,
.mean-low {
    display: inline-block;
    min-width: 58px;
    padding: 2px 7px;
    border-radius: 4px;
    font-weight: 700;
    text-align: center;
    line-height: 1.25;
}

.mean-hit {
    color: #14532d;
    background-color: #dcfce7;
    border: 1px solid #86efac;
}

.mean-near {
    color: #713f12;
    background-color: #fef3c7;
    border: 1px solid #facc15;
}

.mean-high,
.mean-low {
    color: #7f1d1d;
    background-color: #fee2e2;
    border: 1px solid #fca5a5;
}

/* -------- Strategies container (single or compare) ----------------------- */
.strategies-container {
    display: grid;
    gap: 20px;
    margin-bottom: 20px;
}

.strategies-container.is-compare {
    grid-template-columns: 1fr 1fr;
}

@media (max-width: 900px) {
    .strategies-container.is-compare {
        grid-template-columns: 1fr;
    }
}

/* -------- Strategy panel ------------------------------------------------- */
.strategy-panel {
    border: 1px solid var(--border-light);
    border-radius: 8px;
    padding: 18px 20px;
    background-color: var(--card-bg);
    min-width: 0;
    overflow: hidden;
}

.strategy-panel.panel-a {
    border-top: 4px solid var(--strat-a-color);
}

.strategy-panel.panel-b {
    border-top: 4px solid var(--strat-b-color);
}

.strategy-header {
    display: flex;
    align-items: center;
    gap: 10px;
    margin-bottom: 15px;
    padding-bottom: 10px;
    border-bottom: 1px solid var(--border-light);
}

.strategy-badge {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    width: 30px;
    height: 30px;
    border-radius: 50%;
    color: #ffffff;
    font-weight: 700;
    font-size: 1em;
    flex-shrink: 0;
}

.strategy-panel.panel-a .strategy-badge { background-color: var(--strat-a-color); }
.strategy-panel.panel-b .strategy-badge { background-color: var(--strat-b-color); }

.strategy-title {
    flex: 1;
    font-size: 1.15em;
    color: var(--primary-color);
    margin: 0;
}

.strategy-label-input {
    flex: 2;
    min-width: 150px;
    padding: 6px 10px;
    border: 1px solid var(--border-light);
    border-radius: 5px;
    font-size: 0.9em;
    font-family: inherit;
    color: var(--text-dark);
}

.strategy-label-input:focus {
    outline: none;
    border-color: var(--secondary-color);
    box-shadow: 0 0 0 3px rgba(52, 152, 219, 0.15);
}

/* -------- Lignes de médicament ------------------------------------------- */
.med-rows {
    display: flex;
    flex-direction: column;
    gap: 6px;
    margin-bottom: 10px;
}

.med-row {
    display: grid;
    grid-template-columns: minmax(0, 2.2fr) minmax(0, 1fr) minmax(0, 60px) minmax(0, 60px) minmax(0, 60px) 30px;
    gap: 6px;
    align-items: center;
    padding: 6px 8px;
    background-color: var(--card-bg);
    border: 1px solid var(--border-light);
    border-radius: 6px;
    transition: background-color 0.2s;
}

.is-compare .med-row {
    grid-template-columns: minmax(0, 1.6fr) minmax(0, 0.9fr) minmax(0, 50px) minmax(0, 50px) minmax(0, 50px) 28px;
    gap: 4px;
    padding: 6px;
}

.med-row.is-active {
    background-color: #f8fbfe;
    border-color: #cfe3f6;
}

.med-row-header {
    background-color: transparent;
    border: none;
    padding: 0 8px;
    font-size: 0.78em;
    font-weight: 600;
    color: var(--text-muted);
    text-transform: uppercase;
    letter-spacing: 0.4px;
}

.med-row-header .col-dose,
.med-row-header .col-intake {
    text-align: center;
}

.col-intake-header {
    display: flex;
    flex-direction: column;
    align-items: center;
    gap: 2px;
}

.col-intake-header .slot-label {
    font-size: 0.8em;
    color: var(--text-muted);
}

.col-intake-header .slot-hour {
    width: 100%;
    padding: 2px 4px;
    font-size: 0.78em;
    font-family: inherit;
    text-align: center;
    border: 1px solid var(--border-light);
    border-radius: 4px;
    background-color: #ffffff;
    color: var(--text-dark);
    box-sizing: border-box;
}

.col-intake-header .slot-hour:focus {
    outline: none;
    border-color: var(--secondary-color);
    box-shadow: 0 0 0 2px rgba(52, 152, 219, 0.15);
}

.med-row select,
.med-row input[type="number"] {
    width: 100%;
    padding: 6px 8px;
    border: 1px solid var(--border-light);
    border-radius: 4px;
    font-size: 0.9em;
    font-family: inherit;
    color: var(--text-dark);
    background-color: #ffffff;
    box-sizing: border-box;
}

.med-row input[type="number"] {
    text-align: center;
}

.med-row select:focus,
.med-row input[type="number"]:focus {
    outline: none;
    border-color: var(--secondary-color);
    box-shadow: 0 0 0 2px rgba(52, 152, 219, 0.15);
}

.btn-del-row {
    width: 30px;
    height: 30px;
    border-radius: 50%;
    border: 1px solid var(--border-light);
    background-color: #ffffff;
    color: var(--text-muted);
    font-size: 0.9em;
    line-height: 1;
    cursor: pointer;
    padding: 0;
    transition: background-color 0.15s, color 0.15s, border-color 0.15s;
}

.btn-del-row:hover {
    background-color: #fdecea;
    border-color: #e74c3c;
    color: #c0392b;
}

.btn-add-row {
    display: inline-block;
    padding: 8px 14px;
    background-color: transparent;
    color: var(--secondary-color);
    border: 1px dashed var(--secondary-color);
    border-radius: 5px;
    font-size: 0.9em;
    font-family: inherit;
    cursor: pointer;
    transition: background-color 0.15s;
}

.btn-add-row:hover {
    background-color: rgba(52, 152, 219, 0.08);
}

/* -------- Buttons -------------------------------------------------------- */
.form-actions {
    display: flex;
    gap: 12px;
    margin-top: 20px;
    flex-wrap: wrap;
    justify-content: flex-end;
}

.btn {
    padding: 10px 20px;
    border: none;
    border-radius: 5px;
    font-size: 0.95em;
    font-weight: 600;
    cursor: pointer;
    font-family: inherit;
    transition: background-color 0.15s, transform 0.08s;
}

.btn:active {
    transform: scale(0.98);
}

.btn:disabled {
    opacity: 0.6;
    cursor: not-allowed;
}

.btn-primary {
    background-color: var(--secondary-color);
    color: #ffffff;
}

.btn-primary:hover:not(:disabled) {
    background-color: #2e86c1;
}

.btn-secondary {
    background-color: var(--card-bg);
    color: var(--text-dark);
    border: 1px solid var(--border-light);
}

.btn-secondary:hover:not(:disabled) {
    background-color: var(--light-bg);
}

.btn-danger {
    background-color: var(--danger-color);
    color: #ffffff;
}

.btn-danger:hover:not(:disabled) {
    background-color: #c0392b;
}

/* -------- Results -------------------------------------------------------- */
.results {
    margin-top: 30px;
    padding-top: 20px;
    border-top: 2px solid var(--border-light);
}

.results h2 {
    color: var(--primary-color);
    font-size: 1.4em;
    margin-bottom: 18px;
    padding-bottom: 8px;
    border-bottom: 2px solid var(--secondary-color);
}

.results h3 {
    color: var(--primary-color);
    font-size: 1.1em;
    margin: 20px 0 12px;
}

/* -------- Charts row ----------------------------------------------------- */
.charts-row {
    display: grid;
    gap: 16px;
}

.charts-row.is-compare {
    grid-template-columns: 1fr 1fr;
}

@media (max-width: 900px) {
    .charts-row.is-compare {
        grid-template-columns: 1fr;
    }
}

.chart-panel {
    background-color: #fafbfc;
    border: 1px solid var(--border-light);
    border-radius: 6px;
    padding: 12px;
    position: relative;
}

.chart-panel.panel-a { border-top: 3px solid var(--strat-a-color); }
.chart-panel.panel-b { border-top: 3px solid var(--strat-b-color); }

.chart-panel-title {
    font-size: 0.95em;
    font-weight: 600;
    color: var(--primary-color);
    margin-bottom: 8px;
    padding: 0 4px;
    display: flex;
    align-items: center;
    gap: 8px;
}

.chart-panel-title .badge-inline {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    width: 22px;
    height: 22px;
    border-radius: 50%;
    color: #ffffff;
    font-weight: 700;
    font-size: 0.75em;
    flex-shrink: 0;
}

.chart-panel.panel-a .badge-inline { background-color: var(--strat-a-color); }
.chart-panel.panel-b .badge-inline { background-color: var(--strat-b-color); }

.badge-inline.badge-a { background-color: var(--strat-a-color); }
.badge-inline.badge-b { background-color: var(--strat-b-color); }

.stats-block.panel-a .badge-inline { background-color: var(--strat-a-color); }
.stats-block.panel-b .badge-inline { background-color: var(--strat-b-color); }

.chart-wrapper {
    position: relative;
    height: 340px;
    width: 100%;
}

/* -------- Stats row ------------------------------------------------------ */
.stats-row {
    display: grid;
    gap: 16px;
    margin-bottom: 15px;
}

.stats-row.is-compare {
    grid-template-columns: 1fr 1fr;
}

@media (max-width: 900px) {
    .stats-row.is-compare {
        grid-template-columns: 1fr;
    }
}

.stats-block {
    background-color: #fafbfc;
    border: 1px solid var(--border-light);
    border-radius: 6px;
    padding: 12px;
}

.stats-block.panel-a { border-top: 3px solid var(--strat-a-color); }
.stats-block.panel-b { border-top: 3px solid var(--strat-b-color); }

.stats-block-title {
    font-size: 0.9em;
    font-weight: 600;
    color: var(--primary-color);
    margin-bottom: 10px;
    display: flex;
    align-items: center;
    gap: 8px;
}

.stats-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(120px, 1fr));
    gap: 10px;
}

.stat-card {
    background-color: #ffffff;
    border: 1px solid var(--border-light);
    border-radius: 6px;
    padding: 10px 12px;
}

.stat-card.stat-diff-better { background-color: #d4edda; border-color: #c3e6cb; }
.stat-card.stat-diff-worse  { background-color: #f8d7da; border-color: #f5c6cb; }

.stat-label {
    font-size: 0.75em;
    color: var(--text-muted);
    text-transform: uppercase;
    letter-spacing: 0.5px;
    margin-bottom: 4px;
}

.stat-value {
    font-size: 1.3em;
    font-weight: 700;
    color: var(--primary-color);
}

.stat-unit {
    font-size: 0.65em;
    font-weight: 400;
    color: var(--text-muted);
    margin-left: 3px;
}

.stats-empty {
    color: var(--text-muted);
    font-style: italic;
    text-align: center;
    padding: 14px;
    margin: 0;
}

/* -------- Interp row ----------------------------------------------------- */
.interp-row {
    display: grid;
    gap: 16px;
}

.interp-row.is-compare {
    grid-template-columns: 1fr 1fr;
}

@media (max-width: 900px) {
    .interp-row.is-compare {
        grid-template-columns: 1fr;
    }
}

.interpretation-box {
    padding: 14px 18px;
    border-radius: 6px;
    font-size: 0.9em;
    line-height: 1.55;
    border-left: 4px solid var(--info-color);
    background-color: #f4ecf7;
    color: #4a235a;
}

.interpretation-box.empty {
    background-color: #f8f9fa;
    color: var(--text-muted);
    border-left-color: var(--border-light);
    font-style: italic;
}

.interpretation-box.low {
    background-color: #d4edda;
    color: #155724;
    border-left-color: var(--success-color);
}

.interpretation-box.moderate {
    background-color: #fff3cd;
    color: #7a5c00;
    border-left-color: var(--warning-color);
}

.interpretation-box.high {
    background-color: #f8d7da;
    color: #721c24;
    border-left-color: var(--danger-color);
}

.interpretation-box.mixed {
    background-color: #e8e0f0;
    color: #4a2b7a;
    border-left-color: #7b5ea7;
}

.mixed-strategy-error {
    background: #f8d7da;
    color: #721c24;
    border: 2px solid #f5c6cb;
    border-radius: 6px;
    padding: 14px 18px;
    margin: 10px 0 8px 0;
    font-size: 0.9em;
    line-height: 1.6;
}

.compare-cross-class-warning {
    background: #fff3cd;
    color: #7a5c00;
    border: 2px solid #ffc107;
    border-radius: 6px;
    padding: 12px 18px;
    margin: 10px 0 14px 0;
    font-size: 0.9em;
    line-height: 1.6;
}

.interp-block-title {
    font-size: 0.85em;
    font-weight: 600;
    margin-bottom: 6px;
    display: flex;
    align-items: center;
    gap: 6px;
}

/* -------- Disclaimer détaillé -------------------------------------------- */
.disclaimer-detailed {
    margin-top: 30px;
    padding: 20px;
    background-color: #fdecea;
    border-left: 5px solid var(--danger-color);
    border-radius: 6px;
}

.disclaimer-detailed h2 {
    color: #722b27;
    font-size: 1.2em;
    margin-bottom: 12px;
}

.disclaimer-detailed ul {
    list-style: none;
    padding: 0;
    margin: 0;
}

.disclaimer-detailed li {
    padding: 8px 0 8px 24px;
    font-size: 0.9em;
    line-height: 1.5;
    color: #4a1a18;
    position: relative;
}

.disclaimer-detailed li::before {
    content: "•";
    position: absolute;
    left: 8px;
    color: var(--danger-color);
    font-weight: bold;
    font-size: 1.2em;
    line-height: 1;
    top: 10px;
}

.disclaimer-detailed li strong {
    color: #722b27;
}

/* -------- Footer --------------------------------------------------------- */
.page-footer {
    margin-top: 30px;
    padding-top: 20px;
    border-top: 1px solid var(--border-light);
    text-align: left;
    font-size: 0.85em;
    color: var(--text-muted);
}

.page-footer p {
    margin: 10px 0 4px;
}

.page-footer .refs-list {
    margin: 0 0 10px 20px;
    padding: 0;
    list-style: disc;
}

.page-footer .refs-list li {
    margin-bottom: 4px;
    line-height: 1.4;
}

.pk-table-wrap {
    overflow-x: auto;
    margin: 8px 0 12px;
}

.pk-summary {
    border-collapse: collapse;
    width: 100%;
    font-size: 0.95em;
    background-color: var(--surface, #ffffff);
    margin: 12px 0;
    border: 2px solid #546e7a;
}

.pk-summary caption {
    caption-side: top;
    text-align: left;
    font-style: italic;
    padding: 0 0 6px;
    color: var(--text-muted);
}

.pk-summary th,
.pk-summary td {
    border: 1px solid #90a4ae;
    padding: 6px 8px;
    vertical-align: top;
    text-align: left;
}

.pk-summary thead th,
.pk-summary th {
    background-color: #e8f0fe;
    color: var(--text-color, #222);
    font-weight: 600;
    border: 1px solid #546e7a;
}

.pk-summary thead {
    border-bottom: 2px solid #546e7a;
}

.pk-summary tbody tr:nth-child(odd) td {
    background-color: #f7fafd;
}

.pk-summary .pk-model-row td {
    background-color: rgba(24, 95, 165, 0.08);
    border-top: 2px solid #185fa5;
}

.page-footer .pk-sources-note {
    margin-top: 12px;
}

/* -------- PDF Loading overlay -------------------------------------------- */
.pdf-loading {
    position: fixed;
    inset: 0;
    background-color: rgba(0, 0, 0, 0.5);
    display: flex;
    align-items: center;
    justify-content: center;
    z-index: 1000;
}

.pdf-loading[hidden] {
    display: none;
}

.pdf-loading-box {
    background-color: #ffffff;
    padding: 30px 40px;
    border-radius: 8px;
    text-align: center;
    box-shadow: 0 4px 20px rgba(0, 0, 0, 0.2);
}

.pdf-loading-box p {
    margin-top: 16px;
    color: var(--text-dark);
    font-weight: 500;
}

.pdf-spinner {
    width: 40px;
    height: 40px;
    border: 4px solid var(--light-bg);
    border-top-color: var(--secondary-color);
    border-radius: 50%;
    margin: 0 auto;
    animation: spin 0.8s linear infinite;
}

@keyframes spin {
    to { transform: rotate(360deg); }
}

/* -------- Responsive ----------------------------------------------------- */
@media (max-width: 600px) {
    body {
        padding: 10px;
    }

    .container {
        padding: 20px 16px;
    }

    header h1 {
        font-size: 1.4em;
    }

    .form-grid {
        grid-template-columns: 1fr 1fr;
    }

    .med-row {
        grid-template-columns: 1fr 1fr 60px 60px 60px 30px;
        font-size: 0.85em;
    }
    .med-row-header {
        display: none;
    }

    .chart-wrapper {
        height: 280px;
    }

    .form-actions {
        flex-direction: column;
    }

    .form-actions .btn {
        width: 100%;
    }
}